SLICE® is an aquaculture premix containing emamectin benzoate and is only available through Merck Animal Health. SLICE® premix can be purchased through Merck Animal Health and sent to an aquaculture feed mill for top coating. The primary goal of field studies conducted under INAD #11-370 is to evaluate the efficacy of SLICE®-medicated feed and safety of SLICE® to control mortality caused by external parasites in a variety of freshwater and marine fish species. The treatment option that is allowed to administer SLICE® in feed is 50 µg EB per kg of fish biomass per day for 7 consecutive days, and the investigational withdrawal period for treated fish is 60 days. Note: SLICE doesn’t usually reach fully efficacy until 25-35 days after treatment depending on water temperature. This INAD requires all participants to be approved by the FDA Environmental Team prior to participation – this review will take 100 days. To participate in the INAD Program for SLICE® visit the  data collecting site.

Please read the Study Protocol prior to any treatments. It contains the protocol, SDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson. Disinfectants

Merck Animal Health 35500 W. 91st Street De Soto , KS 66018 United States

50 micrograms (μg) emamectin benzoate per kilogram (kg) of fish biomass per day

Investigator must collect mortality data throughout the 5 day pre-treatment, treatment, and 28 day post-treatment periods. Note: SLICE doesn't usually reach fully efficacy until 20-30 days after treatment depending on water temp. The case history and analyses of parasite load needs to be checked both pre- and post-treatment. Investigator must also report general fish behavior and any adverse effects relating to treatment.

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